30 Best Vitamins and Supplements for Drug and Alcohol Detox

Published: 08/19/2025
Blueberries and vitamins

If you’re ready to detox from drugs and alcohol, you’re making a serious positive change for your health. The detox process can be taxing on the mind and the body, and thankfully, taking supplements and vitamins designed to support the body throughout this process can help.

Here, we’ll explore some of the vitamins and supplements that can help you feel your best as you begin your sobriety.

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Why Vitamins Are Crucial During Detox

Substance use can severely impair the body’s ability to absorb and utilize nutrients.

Chronic drinking, for instance, damages the gastrointestinal tract, liver, and pancreas, interfering with digestion and nutrient absorption. Similarly, stimulant and opioid abuse often suppress the appetite and degrade cellular health, leaving the body nutritionally depleted.

Understanding which vitamins alcohol depletes can be helpful for proper recovery. Micronutrients are vital for repairing systems damaged by addiction.

B-vitamins help restore nervous system health, while antioxidants like vitamin C and E combat oxidative stress caused by substance metabolism. Vitamins D and K play roles in mood stabilization, bone health, and immune function.

Choosing vitamins that help with withdrawal symptoms and taking the right vitamins for addiction recovery may support you in regaining health.

Best Vitamins for Alcohol Detox and Withdrawal

If you’ve decided to stop drinking, it’s important to do so with the help of a medical professional, as withdrawal symptoms from alcohol can be dangerous.

Your doctor may recommend that you take vitamins or supplements to help you through the withdrawal period. The following are some of the most commonly recommended vitamins and supplements for people who are in the process of detoxing from alcohol.

An important note: Any supplements used for detox are most effective when taken in conjunction with a healthy diet and plenty of water. Your treatment team will work with you to ensure that you’re getting what you need to support the detox process, one day at a time.

B-Vitamin Complex (B1, B6, B12, B9) B1 (Thiamine)

Chronic alcohol use depletes B vitamins, leading to serious complications. Thiamine (B1) deficiency, for instance, can cause Wernicke-Korsakoff syndrome, a potentially fatal neurological disorder.

Folate (B9) supports DNA repair and red blood cell formation, both impaired by alcoholism. Vitamins B6 and B12 aid in mood stabilization and neuroregeneration. A vitamin B complex for alcohol withdrawal helps restore these vital nutrients, especially thiamine, folic acid, and B12.

Magnesium and Zinc

alcohol detox
Magnesium supplements can help you regain your energy.

Magnesium levels drop significantly in heavy drinkers, contributing to withdrawal symptoms such as tremors, seizures, and anxiety.

Zinc supports immune function, reduces inflammation, and aids in cognitive recovery. Supplementing with magnesium for alcohol withdrawal and zinc for alcohol withdrawal, alongside amino acids, may help ease symptoms.

Vitamins C and E

Alcohol increases oxidative stress, damaging tissues and weakening immunity. Vitamin C neutralizes free radicals and boosts immune health. Vitamin E supports liver regeneration and acts as a skin-repairing antioxidant, making both vitamin C and E essential during detox.

Vitamins D and K

Vitamin D deficiency is widespread in people recovering from alcohol abuse and is linked to mood disorders and immune dysfunction. Vitamin K supports liver function and blood clotting, both compromised in alcohol-related liver disease.

Taking vitamin D for alcohol recovery and ensuring proper intake of vitamin K may be important for you during the detox process.

Omega-3 Fatty Acids

Omega-3s are powerful anti-inflammatory agents essential for brain health. Supplementation has been shown to reduce cravings and relapse risk in people recovering from alcohol.

Including omega-3 for alcohol recovery in a detox regimen can be helpful to improve recovery outcomes.

Selenium

Selenium has antioxidant properties that help protect the liver and brain from oxidative stress. Chronic alcohol use can result in selenium deficiency, which contributes to liver damage.

Milk Thistle and Kudzu Root

Milk thistle contains silymarin, which may help protect liver cells. Kudzu root has shown some potential to moderately reduce alcohol cravings. More research is needed before milk thistle and kudzu can be considered effective treatments for alcohol use disorder.

NAC (N-Acetylcysteine)

NAC boosts glutathione production—a critical antioxidant for liver functioning. Research suggests it may reduce cravings. The strongest evidence supports its use for cannabis use disorder. Early studies suggest benefits for alcohol detox. Though it is not a substitute for medical treatment, using NAC is an option for alcohol cravings.

Taurine

Taurine helps regulate the GABA system, which can become imbalanced during alcohol withdrawal. It also has calming properties and may help prevent seizures. Taurine for alcohol withdrawal may be useful in calming the nervous system.

Multivitamins

Multivitamins can help replace some of the broad nutrient deficiencies caused by alcohol abuse. They offer support across systems, from immunity to cognition. Taking a multivitamin can provide a baseline nutritional foundation during detox.

Best Vitamins for Drug Detox

Substance use disorders are varied, as are the supplementary treatments that are most effective. The vitamins that work best for drug detox are sometimes different from those that work well for alcohol detox.

Core Vitamins for All Drugs

No matter the substance, drug detox depletes essential nutrients. Vitamins C and E combat oxidative stress, while magnesium and calcium support muscle and nerve recovery. A daily multivitamin and B-complex replenish what’s lost during detox. These vitamins are often considered foundational drug detox supplements.

For Meth and Stimulants (Cocaine, Adderall)

L-tyrosine may support dopamine production after stimulant abuse. B6 and B12 contribute to neurorepair and energy. CoQ10 supports mitochondrial function and cellular recovery. For meth recovery, these supplements can be part of a supportive regimen.

For Opioid & Heroin Detox

Opioid withdrawal brings mood instability and physical discomfort. Vitamin C and B-vitamins support the immune and nervous systems, while magnesium and taurine may help calm muscles. L-glutamine supports neurotransmitter function and gut health. These supplements for heroin recovery can aid both physical and emotional resilience.

For Marijuana / THC Detox

Garlic contains compounds that support liver function, which may aid the body’s natural detox processes. Niacin and vitamin C also help support the liver’s processes in clearing THC.

Emotional and Craving Support Supplements

While the physical effects of detox and the start of recovery can be intense, the emotional cravings can make it just as hard to stay sober. Thankfully, supplements can help with mood, anxiety, depression, and other emotional and mental health issues that can make it harder to stay sober.

Supplements like NAC and omega-3s may help reduce cravings. GABA, inositol, and 5-HTP may help to reduce anxiety, promote sleep, and stabilize mood. These supplements are sometimes used to reduce alcohol cravings.

An important note: while these supplements can support your mental health, they don’t take the place of talking with a therapist or counselor who can support you throughout your recovery.

Safe Supplementation During Detox

While vitamins can support the body’s detox processes, supplementation must be done safely. Follow these tips to ensure that you’re using vitamins and other supplements correctly to work through the detox process.

  • Consult a healthcare provider before beginning any regimen.
  • Avoid high doses unless supervised by a medical professional.
  • Introduce supplements gradually to monitor effects.
  • Maintain hydration and seek support through professional medical detox.

When to Seek Help

Supplements can help support detox, but they are not a replacement for treatment. If you’re struggling, consider a rehab program that includes medical supervision and vitamin therapy. These programs combine supplements to quit drinking with counseling and medical care to maximize recovery.

If you’re ready to learn more about rehab options in your area, call today to speak to someone who can help you find the right type of treatment for your unique recovery needs.

Don’t wait to detox. Call today for help.

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Vitamin and Supplement FAQs

What Vitamins Help Detox the Body from Alcohol?

The best vitamins include B-complex (especially B1, B6, and B12), vitamin C, vitamin D, and magnesium. These nutrients support neurological recovery, reduce oxidative stress, and address common deficiencies caused by alcohol use.

Which Vitamins are Best for Alcohol Withdrawal Symptoms?

The best vitamins for alcohol withdrawal symptoms include:

-Thiamine (B1) to prevent brain damage like Wernicke-Korsakoff syndrome
-Magnesium to reduce tremors and anxiety
-Vitamin C and E for antioxidant protection
-Folate (B9) and B12 to support mood and nerve repair

These vitamins for alcohol withdrawal can ease symptoms such as irritability, insomnia, and fatigue.

Can Supplements Reduce Alcohol Cravings?

Yes. Certain supplements, such as NAC (N-cetylcysteine), omega-3 fatty acids, magnesium, and B6, may help reduce cravings by supporting healthy neurotransmitter function. Supplements to reduce alcohol cravings work best when used alongside behavioral therapy and medical detox.

What Vitamins Do Alcoholics Need to Recover?

Recovering alcoholics may benefit from:

-Vitamin B complex for alcohol withdrawal
-Vitamin D for bone and immune health
-Magnesium for relaxation and sleep
-Omega-3s for mood regulation
-Milk thistle to support liver regeneration

Knowing which vitamins alcohol depletes helps guide targeted supplementation for full recovery.

Are There Natural Vitamins that Help You Stop Drinking?

While no vitamin alone can stop a person from drinking, natural supplements for alcohol withdrawal like kudzu root, NAC, inositol, and milk thistle may help reduce cravings and support detox. These should be used under medical supervision and alongside counseling or treatment.

What are the Best Vitamins for Drug Detox?

B-complex, vitamin C, magnesium, CoQ10, and amino acids like L-tyrosine and glutamine can all support health during drug detox for some individuals.

Do B Vitamins Help with Withdrawal?

Absolutely. Vitamin B complex can play an important role in alcohol withdrawal. B1 helps prevent brain damage, B6 supports serotonin production, and B12 aids in nerve health. They are essential vitamins that may help with withdrawal symptoms and may improve energy and cognition in early recovery.

Can You Use Milk Thistle During Alcohol Detox?

Yes, milk thistle may help support liver regeneration and detox.

What Vitamins Support Liver Recovery from Alcohol Abuse?

Vitamin C, E, selenium, milk thistle, and NAC can all support your liver as it heals following alcohol abuse.

Is Magnesium Effective for Alcohol Withdrawal Anxiety?

Yes. Magnesium for alcohol withdrawal can be effective for some people in calming the nervous system. It may reduce anxiety, support sleep, and help control tremors.

What Role Does Vitamin C Play in Addiction Recovery?

Vitamin C reduces oxidative stress and boosts immune function.

Are There Vitamins that Help with Meth or Opioid Detox?

Yes. For methamphetamine and stimulant recovery, L-tyrosine, B12, and CoQ10 support dopamine restoration and mitochondrial health. For opioid detox, magnesium, taurine, vitamin C, and B-complex may help ease withdrawal symptoms and support neurotransmitter repair.

Can Niacin or Kudzu Help with Alcohol Cravings?

Yes, studies suggest both may help in managing cravings.

Should You Take a Multivitamin After Quitting Alcohol?

Yes. A high-quality multivitamin can help correct multiple deficiencies in people who have been consuming alcohol. However, for therapeutic effects, additional targeted supplements like thiamine or magnesium may be necessary during early recovery.

What Vitamins Flush Toxins from the Body?

Vitamin C, B-complex, and antioxidants like NAC and selenium support the body’s natural detox processes.

Have More Questions About Detox?

Learn more about support during drug or alcohol detox and effective treatment options. Call the number below to speak with someone about substance detox.

Call today to find detox centers and begin your recovery.

800-996-6135
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Written by: Courtney Myers

MS

Courtney Myers writes and edits professionally from her home in North Carolina. She holds an MS in Technical Communication from N.C. State University and has worked in proposal management, marketing, and online content creation. She specializes in creating resources related to behavioral health and addiction recovery.

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