Pennsylvania Trial to Test Ozempic for Alcohol and Opioid Addiction

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Published: 10/27/2026
ozempic and addiction treatment

A study planned for next year will test whether GLP-1 medicines like Ozempic can reduce alcohol and opioid use when added to existing care. It’s being led by Allegheny County’s Department of Human Services in partnership with the Center for Addiction Science, Policy and Research

The trial is going to include 1,200 participants and is expected to cost around $13 million. Researchers from MIT, the University of Pittsburgh, the University of California San Diego and UPMC Western Psychiatric Hospital are involved.

What the Allegheny County Study Will Measure

The medicines will be given in conjunction with the participants’ regular addiction treatment. County DHS director Alex Jutca said researchers want to learn whether the medicines help clients control cravings and reduce drug and alcohol consumption. And in the end, they’ll lead healthier lives.

The study is also expected to look at outcomes beyond substance use. Allegheny County maintains detailed records about people who use its services. This lets researchers assess employment, health, housing and involvement with the criminal justice system. Jutca described that broader analysis as a holistic view of possible benefits of the treatment plan.

Previous research into the benefits of these weight management medicines suggests they might also be effective in treating alcohol or drug disorders. This trial is intended to build on that work.

What This Means for Patients

Experts hope that the medicines might be effective in managing cravings and easing withdrawal symptoms. That might also reduce the risk of relapse over the long term.

The Allegheny County design is notable because participants keep their existing treatment. That allows researchers to examine GLP-1 medication as an addition to care rather than assuming it can replace therapy, medication-assisted treatment or withdrawal supervision.

Finding Medical Detox in Pennsylvania

Detox.com lists medical detox and drug detox programs by location, including Pennsylvania options. You can search for the program that best meets your needs, including outpatient options and services for special populations. Call 800-996-6135 to get more information.

Written by: Courtney Myers

MS

Courtney Myers writes and edits professionally from her home in North Carolina. She holds an MS in Technical Communication from N.C. State University and has worked in proposal management, marketing, and online content creation. She specializes in creating resources related to behavioral health and addiction recovery.

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Reviewed by: Eric Owens

Eric has a passion for content creation, whether it’s writing articles or making YouTube videos. He appreciates the power of storytelling to inform an audience about the information they need to know. In addition to writing, he also spends his time traveling and discovering new restaurants.

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