Find Drug & Alcohol Detox Centers in Sioux Falls, SD

Detox Centers in Sioux Falls

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Name Address Detox Service Setting Levels Of Care Media

Avera Behavioral Health Hospital

4400 West 69th Street Sioux Falls, SD 57108
Detox Service Setting
Inpatient DetoxOutpatient DetoxMAT
Levels Of Care
InpatientPHPOutpatient+3
Avera Behavioral Health Hospital

Avera Medical Group Family Health Center – Marion Road

2100 South Marion Road Sioux Falls, SD 57106
Detox Service Setting
Inpatient DetoxOutpatient DetoxHospital Detox+1
Levels Of Care
InpatientOutpatientPHP
Avera Medical Group Family Health Center – Marion Road

Keystone Treatment Center – Sioux Falls

3800 S Kiwanis Ave Sioux Falls, SD 57105
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatient

Prairie View Prevention Services

822 E 41st St Sioux Falls, SD 57105
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatient

New Life Treatment Woodstock

130 Dakota Street South Woodstock, MN 56186
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatientAftercare+1
New Life Treatment Woodstock

Stepping Stones Rehabilitation Services

901 South Miller Avenue Mitchell, SD 57301
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatientAftercare+2
Stepping Stones Rehabilitation Services

Rosecrance Jackson Centers Women’s Center

3200 West 4th Street Sioux City, IA 51103
Detox Service Setting
Inpatient DetoxOutpatient DetoxMAT
Levels Of Care
InpatientPHPOutpatient+4
Rosecrance Jackson Centers Women’s Center

Jackson Recovery Centers Synergy Center

1267 West Cedar Loop Cherokee, IA 51012
Detox Service Setting
Inpatient DetoxOutpatient DetoxMAT
Levels Of Care
InpatientPHPOutpatient+2
Jackson Recovery Centers Synergy Center

Mayo Clinic Health System

1101 Moulton And Parsons Drive Saint James, MN 56081
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatientAftercare+1
Mayo Clinic Health System

Oasis Counseling International Norfolk

333 West Norfolk Avenue Norfolk, NE 68701
Detox Service Setting
Outpatient Detox
Levels Of Care
OutpatientAftercareDual Diagnosis
Oasis Counseling International Norfolk

Behavioral Health Specialists – Sunrise Place

1900 Vicki Lane Norfolk, NE 68701
Detox Service Setting
Inpatient Detox
Levels Of Care
InpatientIntensive OutpatientOutpatient
Behavioral Health Specialists – Sunrise Place

Sunrise Place Residential Treatment

1900 Vicki Lane Norfolk, NE 68701
Detox Service Setting
Inpatient Detox
Levels Of Care
InpatientDual Diagnosis
Sunrise Place Residential Treatment

Mayo Clinic Health System Fairmont Behavioral Health

800 Medical Center Drive Fairmont, MN 56031
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatientAftercare+1
Mayo Clinic Health System Fairmont Behavioral Health

Valley Hope of O Neill

1421 North 10th Street Oneill, NE 68763
Detox Service Setting
Inpatient DetoxMAT
Levels Of Care
InpatientAftercareDual Diagnosis+1
Valley Hope of O Neill

Allina Health Outpatient Addiction Services New Ulm Medical Center

1324 5th Street North New Ulm, MN 56073
Detox Service Setting
Inpatient DetoxOutpatient Detox
Levels Of Care
InpatientOutpatientDual Diagnosis
Allina Health Outpatient Addiction Services New Ulm Medical Center

Drug & Alcohol Detox in Sioux Falls, SD

Sioux Falls holds the largest concentration of treatment options in South Dakota, covering the full continuum from hospital-based medical detox through residential programs, intensive outpatient and dedicated opioid treatment programs. This is especially important because methamphetamine is the most commonly involved substance in drug offenses statewide, while fentanyl drives most fatal overdoses.

The city’s most notable recent addition is The Link, a 24/7 low-barrier stabilization center at 132 North Dakota Avenue, operated by Avera Health in partnership with the City of Sioux Falls and Minnehaha County. Importantly, The Link provides immediate triage for people experiencing acute intoxication, withdrawal symptoms or mental health crises, without requiring an appointment or insurance.

Moreover, opioid settlement funds are reshaping the local treatment capacity. For example, in April 2026, South Dakota announced $7.8 million in grants, including $3 million to Avera Behavioral Health for adolescent addiction services and $1 million to the Sioux Falls School District for substance use interventionists in schools.

South Dakota’s Division of Behavioral Health (DBH), a division of the Department of Social Services, licenses and accredits all substance use disorder treatment facilities in the state. In fact, DBH accreditation is required for Medicaid enrollment and state grant eligibility, so any accredited program has met standardized clinical and safety standards.

As well, the South Dakota Board of Addiction and Prevention Professionals (BAPP), also within DSS, separately licenses the individual addiction counselors who deliver care at those facilities.

Find The Perfect Detox Center For You

Filter treatment centers in Sioux Falls by level of care offered to find the best detox program for you or a loved one.

Paying for Detox in Sioux Falls

Detox costs in Sioux Falls vary based on the level of care, the substances involved, medical complexity and length of stay. Most treatment centers accept private insurance, Medicaid, and Medicare and several offer sliding fee scales or state-funded assistance for uninsured residents.

How Much Does Detox Cost in Sioux Falls?

The cost of medical detox in Sioux Falls depends heavily on whether care is delivered in a hospital, a residential facility or an outpatient setting.

Hospital-based programs carry the highest cost because of around-the-clock physician and nursing oversight. Though outpatient programs are significantly more affordable. Finally, medication-assisted treatment is typically the most cost-accessible option for many people.

Sioux Falls-specific pricing data is limited; the figures below reflect South Dakota and national averages and should be confirmed with individual providers.

Outpatient MAT combines prescribed medication with counseling and monitoring, and allows most people to maintain daily responsibilities during treatment.

Keep in mind that MAT costs vary based on which medication is prescribed and whether your insurance covers it.

$150,000
Medical Detox
$53,000
Inpatient Rehab
$11,000
Outpatient Rehab
$5,200
Methadone Treatment

Does Private Insurance Cover Detox in Sioux Falls?

Under the Affordable Care Act, private insurers are required to cover substance use disorder treatment at parity with other medical benefits. South Dakota’s Division of Insurance oversees plan compliance within the state. Residents can compare marketplace plans at HealthCare.gov.

The most commonly used private insurers in Sioux Falls include:

Wellmark
United Health Care
Cigna
Medica

Medicare and Medicaid in Sioux Falls

Medicare

Medicare covers both inpatient and outpatient alcohol and drug detox in Sioux Falls. Part B also covers opioid treatment program (OTP) services, including methadone, buprenorphine and naltrexone. Copays and deductibles vary depending on the treatment setting, specific services received and your plan type.

Medicaid

South Dakota expanded Medicaid in July 2023, significantly broadening coverage for low-income adults. South Dakota Medicaid covers inpatient detox, residential treatment, outpatient services, and MAT, including methadone, buprenorphine and naltrexone. There are no copays required for substance use disorder treatment under South Dakota Medicaid.

Other Ways to Pay for Detox Treatment

Do not let cost prevent you from seeking care in Sioux Falls. Several local and state programs provide financial support for people who cannot afford private insurance or the full cost of treatment. For example:

Sliding Scale Payment Systems

Glory House and Volunteers of America Dakotas both offer sliding fee scales tied to income and federal poverty guidelines and Volunteers of America Dakotas also accepts Access to Recovery (ATR) vouchers to offset the cost of care.

State Indigent Medication Program

The South Dakota Department of Social Services operates an Indigent Medication Program that provides temporary financial support for uninsured residents who need medication to treat substance use disorders, including MAT for both opioid use disorder and alcohol use disorder.

Veterans Programs

The Sioux Falls VA Health Care System provides comprehensive addiction treatment services for eligible veterans through its behavioral health programs. Volunteers of America Dakotas also operates a Veterans Services Center in downtown Sioux Falls with VA referrals, housing resources and connections to addiction support.

Local Opioid Settlement Grants

The City of Sioux Falls has directed its local share of opioid settlement funds to The Link’s Opioid Response Program, which provides free crisis stabilization for residents experiencing withdrawal or acute intoxication regardless of insurance status.

Sioux Falls, South Dakota Regulations and Accreditation for Detox

Several primary regulatory and accreditation bodies oversee detox and substance use disorder treatment services in Sioux Falls and South Dakota, including:

Division of Behavioral Health (DBH), SD Department of Social Services

The primary state licensing and accreditation authority for all substance use disorder treatment facilities in South Dakota, including those in Sioux Falls.

DBH accreditation is required for Medicaid enrollment and eligibility for state general fund contracts. Facilities receive provisional accreditation for six months, followed by a comprehensive compliance survey, then annual re-surveys for renewal.

Website: dss.sd.gov

South Dakota Board of Addiction and Prevention Professionals (BAPP)

Also housed within the Department of Social Services, BAPP licenses individual addiction counselors who provide treatment in South Dakota facilities.

Licensure requires specific education, a minimum of 2,000 hours of supervised clinical experience across the twelve core addiction counselor domains and a credentialing exam. This ensures that counselors working in Sioux Falls detox programs meet a consistent statewide standard of practice.

Website: dss.sd.gov

SAMHSA Opioid Treatment Program (OTP) Certification and DEA Registration

At the federal level, SAMHSA certification under 42 CFR Part 8 and DEA Schedule II registration are both required for any facility dispensing methadone for opioid use disorder treatment.

In Sioux Falls, BAART Programs and Sioux Falls Treatment Center hold certified OTP status and carry SAMHSA and DEA certifications. Sioux Falls Treatment Center also holds accreditation from the Commission on Accreditation of Rehabilitation Facilities (CARF), a nationally recognized independent accreditation body.

Website: samhsa.gov

Key MAT Medications and Regulatory Status in Sioux Falls

Medication-assisted treatment in Sioux Falls operates under overlapping federal and state oversight. Under federal OTP rules 42 CFR Part 8 and DEA controlled-substance regulations, methadone programs are governed, while South Dakota DBH licensing standards require behavioral therapy and counseling to accompany medication-assisted detox as part of a complete treatment plan.

Buprenorphine: 

Widely available in Sioux Falls through certified prescribers in primary care and addiction medicine, and via telehealth. No OTP certification is required for prescribers beyond a DEA registration, making buprenorphine the most accessible MAT option for people seeking to start treatment quickly or who prefer outpatient initiation.

Methadone: 

Restricted to SAMHSA-certified OTPs and cannot be dispensed from a standard pharmacy for opioid use disorder treatment. In Sioux Falls, BAART Programs and Sioux Falls Treatment Center are certified OTPs that provide methadone under daily observed dosing protocols, with patients becoming eligible for take-home doses as treatment progresses.

Naltrexone: 

Available by standard prescription with no OTP or special certification requirements for prescribers. The injectable formulation, Vivitrol, is commonly used in Sioux Falls for both opioid use disorder and alcohol use disorder. South Dakota Medicaid covers both oral and injectable naltrexone with no required copayment.

Overdose Prevention and Harm Reduction in Sioux Falls

Sioux Falls has a growing harm reduction network built largely through nonprofit advocacy and state opioid response funding.

This is especially important because overdose deaths in Minnehaha County have risen in recent years, with fentanyl increasingly found in the local drug supply alongside methamphetamine.

Although South Dakota does not have authorized syringe service programs, residents of Sioux Falls can access naloxone for free through multiple channels across the city, and fentanyl test strips are available through local organizations.

These services provide a critical connection point between people who use drugs and the treatment system.

Emily's Hope

Free naloxone distribution boxes at Avera hospital sites Free naloxone at community locations across Sioux Falls Fentanyl test strips Overdose response education Youth prevention curriculum in K-12 schools

Emily’s Hope is a Sioux Falls-based nonprofit founded by Angela Kennecke after her daughter Emily died of fentanyl poisoning in 2018.

In partnership with the South Dakota Departments of Health and Social Services, the organization has distributed more than 40,000 doses of naloxone across South Dakota, with distribution boxes placed in hospital entryways, libraries and other public locations.

Kits include naloxone nasal spray and instructions, require no ID or insurance and are available around the clock.

The Link

24/7 walk-in stabilization for acute intoxication and withdrawal symptoms Mental health crisis triage Nursing assessments and advanced practice provider oversight Case management and connections to detox, ongoing treatment, and naloxone Overdose education at the point of contact

The Link, located at 132 North Dakota Avenue in downtown Sioux Falls, is a 24/7 low-barrier crisis stabilization center operated by Avera Health in partnership with the City of Sioux Falls and Minnehaha County.

No appointment or referral is needed. In fact, people experiencing withdrawal, acute intoxication or mental health crises can walk in at any time to access immediate medical assessment and help connecting to treatment options.

Avoid Opioid SD

Online pharmacy naloxone locator for Sioux Falls and across South Dakota Education on the statewide naloxone standing order Safe medication disposal information Free lock box requests Counterfeit pill and fentanyl awareness resources

Avoid Opioid SD is a joint public health campaign of the South Dakota Departments of Health and Social Services.

Through the site’s pharmacy locator, Sioux Falls residents can find nearby pharmacies that dispense naloxone under the state’s standing order, which allows any person at risk of overdose, or anyone caring for someone at risk, to receive naloxone without an individual prescription.

The site also accepts requests for one free medication lock box per household.

South Dakota Department of Health Naloxone Project

First responder training and naloxone equipment School-based naloxone distribution and training Employer and business distribution program Statewide saturation tracking Coverage gap analysis

Using federal State Opioid Response (SOR) grants, the South Dakota Department of Health Naloxone Project equips emergency services, schools and businesses with naloxone kits and overdose response training.

As of early 2026, the Sioux Falls area had more than 6,200 naloxone medications freely available above the saturation level that national benchmarks recommend, reflecting the scale of recent distribution efforts in Minnehaha and Lincoln counties.

Detox Statistics in Sioux Falls, South Dakota

South Dakota has one of the lowest per-capita overdose death rates in the country, but the statewide numbers have increased in recent years. Unfortunately, Minnehaha County, which contains Sioux Falls, bears a disproportionate share of the burden.

The following statistics reflect the scope of substance use and overdose in the region.

73 Unintentional Overdose Deaths in South Dakota in 2024

South Dakota recorded 73 unintentional and undetermined overdose deaths in 2024, a 12% increase from 65 deaths in 2023.

Methamphetamine Involved in 49% of SD Overdose Deaths

Methamphetamine was identified in 49% of South Dakota’s unintentional overdose deaths from 2020 to 2024, making it the most commonly identified substance in fatal overdoses across those five years.

American Indians Die from Overdose at 4.4x the Rate of White Residents

From 2020 to 2024, American Indians in South Dakota died from drug overdoses at a rate 4.4 times higher than white residents, reflecting a significant and ongoing disparity in overdose outcomes.

FAQs About Detox in Sioux Falls, SD

Does Sioux Falls have a walk-in option for people in acute withdrawal?

Yes. The Link, located at 132 North Dakota Avenue in downtown Sioux Falls, operates 24 hours a day, seven days a week as a low-barrier stabilization center. No appointment, referral or insurance is required.

Staff includes nurses, advanced practice providers, and behavioral health counselors who can assess withdrawal severity and help connect you to detox programs once you are stabilized.

What MAT programs are available in Sioux Falls for opioid use disorder?

Sioux Falls has two SAMHSA-certified opioid treatment programs: BAART Programs Sioux Falls and Sioux Falls Treatment Center, both of which dispense methadone and offer buprenorphine.

Multiple primary care providers and addiction medicine specialists in the city also prescribe buprenorphine, including via telehealth for those with transportation barriers. You should contact providers directly to confirm current availability and wait times.

Does South Dakota Medicaid cover detox for people newly enrolled through the 2023 expansion?

Yes. Since Medicaid expansion took effect in July 2023, South Dakota Medicaid covers inpatient detox, residential treatment, outpatient services and MAT, including methadone, buprenorphine and naltrexone. There are no copays for substance use disorder treatment under the state Medicaid program.

Coverage is available immediately upon enrollment at any DBH-accredited provider that accepts Medicaid.

Are there detox programs in Sioux Falls for pregnant women?

Yes. Volunteers of America Dakotas offers specialized programming for pregnant and postpartum women and the ReNew program provides peer support, housing assistance and substance use treatment specifically for women in recovery during pregnancy and through the first year after birth.

Inpatient detox for pregnant women typically involves close OB coordination and, for those with opioid use disorder, buprenorphine is the preferred medication to manage withdrawal while supporting fetal health.

Is naloxone free and available without a prescription in Sioux Falls?

Yes. Naloxone is available at no cost through Emily’s Hope distribution boxes at Avera hospital locations and other community sites across Sioux Falls.

Through South Dakota’s statewide standing order, pharmacies can dispense naloxone to any person at risk of overdose or to anyone caring for someone at risk, without an individual prescription. For those without insurance, state DSS funding is available to cover the cost.

How does Minnehaha County's overdose situation compare to the rest of South Dakota?

Minnehaha County, which encompasses Sioux Falls, ranks among the ten highest-impact counties in the state for opioid use and overdoses. In fact, drug overdoses became the leading cause of accidental death in the county as of 2026.

Fortunately, the county has received the largest share of local opioid settlement funds in South Dakota and the Sioux Falls area, resulting in proportionally higher naloxone distribution and treatment infrastructure than most rural parts of the state.

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