What is Gabapentin and Why is It Abused?

Covvey is correct in saying that people abuse gabapentin for a variety of reasons.

It can enhance the feelings of euphoria caused by opioids. It can reduce withdrawal effects. And it can allow patients to get high while in recovery, because it can bypass the blocking effects of addiction treatment medications.

What Covvey didn’t mention, however, is that gabapentin misuse comes with some very serious risks: addiction, overdose, and even death.

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What is Gabapentin?

Gabapentin is an anticonvulsant. It’s designed to control nerve impulses, which helps prevent seizures and treat nerve pain. The drug was approved by the FDA in 1993 to treat epilepsy and pain caused by shingles.

It’s sold under the brand name Neurontin and is available in several generic forms.

Since its approval, gabapentin has become a go-to drug for many conditions. Doctors prescribe it to treat migraines, restless leg syndrome, hot flashes, fibromyalgia, and neuropathic pain. Some even prescribe it to treat insomnia and anxiety.

This drug has also been used as part of detox programs. It can help ease the symptoms of withdrawal. Addiction specialists also prescribe gabapentin for pain management in those who are addicted to opioids or at risk of addiction.

With so many uses, it’s easy to see why gabapentin became one of the most widely prescribed drugs by 2016. As of 2021, it was the sixth most prescribed drug in the United States.

Quite a few of its uses, though, are off-label. Doctors are prescribing it for unapproved issues, and many people end up taking it with other drugs that can have deadly interactions.

How is it Abused?

Gabapentin can produce a marijuana-like high or a sense of euphoria or calm. Some users report improved sociability with its use. Others have noted its “zombie-like” effects.

Some researchers suspect that the drug releases neurotransmitters in the brain that affect the reward system. This can lead to addiction.

And the drug is often combined with other abused substances, to increase their effects.

The irony is, gabapentin was supposed to provide a safer alternative to opioids. But now abusers are using it in combination with opioids to increase their high. This abuse is risky. Taking these drugs together significantly increases the risk of opioid overdose.

It increases the risk for respiratory depression, overdose, and death. Combining gabapentin with alcohol or sleep medications (anything that makes you drowsy or slows your breathing) further increase the risk.

But these risks don’t seem to be slowing down gabapentin abuse. Roughly 1% of the general population is estimated to misuse gabapentin. Among those who have prescriptions, 40-65% misuse the medication, and up to 22% of people who abuse opioids also misuse gabapentin.

And it’s partly because it’s so easy to get.

Gabapentin is not labeled as a controlled substance. This means it is not regulated under the federal Controlled Substances Act of 1970. And that means it can be readily available.

So it’s easy to abuse.

Because it is not controlled, there are few to no restrictions on who can possess it and dispense it. This has made it hard for officials to control gabapentin abuse.

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Steps to Reduce Risk

Prescription numbers for gabapentin have continued to climb, and signs of abuse have increased. So, officials are rethinking the limitations on this drug. In 2019, the FDA ordered new warnings of breathing risks on gabapentin labels.

That same year, gabapentin abuse caused so many overdose deaths in Kentucky that the state declared it a controlled substance. Other states have taken the same stance.

These state actions and increased awareness have placed pharmacists on higher alert about the potential risks of gabapentin abuse. Experts recommend that pharmacists take extra care when filling gabapentin prescriptions. Helpful strategies include:

• Pharmacists should check in with patients to see how well the medication is working.
• Re-check in every few months.
• Let prescribers know if the medication isn’t helping, so they can prescribe an alternative.
• Pharmacists may also need to provide additional counseling to those who take gabapentin and other substances that create risky combinations.
• Patients should be warned about the risk of overdose and death.

If you or someone you love is experiencing a substance use disorder, help is available. Call 800-996-6135(Sponsored) today to speak with a treatment specialist.