Kratom Detox and Rehab: Symptoms, Timeline, and Evidence-Based Treatment

Published: 11/10/2025
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Kratom is an herbal substance derived from the leaves of a tree found growing in Southeast Asia. The leaves from this tree contain psychoactive compounds that can produce both stimulant and opioid-like effects. In the U.S., some individuals use kratom for energy, pain relief or to self treat opioid withdrawals. However, rehab for kratom use is on the rise.

Although kratom use is becoming more popular, growing evidence shows that its use can lead to dependence and withdrawal. People often seek rehab from kratom when their use begins to affect their health, relationships or daily functioning.

While marketed as a natural alternative, kratom isnot approved by the U.S Food and Drug Administration (FDA). Furthermore, research from the National Institute on Drug Abuse (NIDA) confirms its addictive potential and associated risks.

This article provides quick answers about detox, withdrawal symptoms, how long kratom stays in your system, detox guidelines and safe treatment settings. It also outlines where to find trusted kratom detox centers offering evidence based care.

Think you’re addicted to kratom? Call now.

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Is Kratom Addictive? What We Know from Research

Yes, kratom can be addictive, according to the National Institute of Drug Abuse (NIDA) and the U.S. Food and Drug Administration (FDA). Kratom acts on bothopioid and stimulant receptors.

Its active alkaloids, mitragynine and 7-hydroxymitragynine, bind to mu-opioid receptors in the brain, producing euphoria and pain relief similar to opioids. However, it is not FDA approved for any medical use. 

Chronic or high dose use can cause tolerance, dependence/addiction and withdrawal, particularly among individuals self medicating for pain or anxiety. According to the Centers for Disease Control (CDC), while fatalities are rare, they often involve polysubstance use.

Surveys conducted by the Substance Abuse and Mental Health Services Administration in 2021 found that an estimated 1.7 million Americans use kratom.

Dependence/withdrawal symptoms may include:

  • Cravings or inability to stop using
  • Irritability, anxiety or restlessness
  • Muscle aches, tremors and insomnia
  • Nausea, vomiting, diarrhea

While kratom may seem harmless, its addictive potential warrants medical oversight during the detox process.


Download our free Kratom Detox Protocol to track symptoms and plan recovery safely. Kratom Detox Protocol: Your Daily Recovery Plan


Rehab for Kratom and Detox Options: Inpatient vs. Outpatient

When exploring kratom detox, the best treatment setting depends on the individual’s level of dependence, physical health and available support system. A licensed kratom detox center can evaluate whether inpatient or outpatient kratom detox treatment is most appropriate. 

Those searching for a kratom detox program should understand that while both approaches aim to help individuals safely stop using kratom, they differ in supervision, structure and intensity. 

When Inpatient Kratom Detox is Safer

Inpatient rehab for kratom addiction is recommended for individuals experiencing severe dependence, polysubstance use, especially with opioids or benzodiazepines, co-occurring medical or psychiatric conditions, unstable living environments or a history of complicated withdrawals.

The inpatient setting offers 24-hour medical care and structured therapy to ensure safe stabilization and transition into further treatment.

When Outpatient Kratom Detox Works

Outpatient treatment may be appropriate for individuals with mild to moderate dependence, have a stable home and support system and will reliably attend follow up appointments and follow medication guidance.

For them, a guided kratom detox protocol or kratom detox plan can often be managed in an outpatient setting with ongoing clinical supervision and medication support.

Some clinical studies suggest that the use of buprenorphine-naloxone may help with kratom withdrawal in select cases, though further research is needed. One program, developed by the Coleman Institute for Addiction Medicine, is an example of this type of outpatient detox.

They use a structured, medication assisted five day detox plan, called The Coleman Method, to help individuals suffering from Kratom addiction.

Kratom Withdrawal Symptoms & Timeline (Quick Reference)

Understanding kratom withdrawal symptoms can help an individual prepare for what’s to come during detox. Because kratom acts on opioid receptors, withdrawal symptoms resemble mild opioid withdrawal and vary in intensity based on usage patterns and overall health.

A timeline for kratom withdrawal and detox, from daily use to cutting use entirely

Typical kratom withdrawal symptoms may include:

  • Anxiety or irritability
  • Restlessness or insomnia
  • Muscle aches, tremors or fatigue
  • Nausea, vomiting or diarrhea
  • Sweating, chills
  • Cravings 
  • Mood swings

The kratom withdrawal timeline generally begins 12-48 hours after the last dose, peaks around 24-72 hours and most symptoms subsiding byday 3-7.

However, in some cases, especially those with long term or high dose use, individuals may experience post acute withdrawal syndrome (PAWS) that can last for several weeks or months.

Kratom is detectable in urine for 5-7 days, in blood for 1-3 days, in saliva for 1-2 days and up to 90 days in hair follicles. The amount of time it takes to clear kratom from the body depends on the frequency and amount used, body composition, hydration level and liver function.

Currently, there are no standard multi-panel toxicology tests for kratom. When screening for kratom, a specialized lab test is required.

Need help detoxing from kratom? Call today.

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Evidence Based Treatments During Kratom Detox

The best way to detox from kratom involves close medical supervision with supportive care that includes evidence based medications and ongoing therapy. 

Medications (Supportive & MOUD where Appropriate)

Medications commonly used during kratom detox include antiemetics for nausea, antidiarrheals, NSAIDs for muscle pain, sleep aids and alpha-2 agonists like clonidine to ease anxiety and agitation.

For individuals with moderate to severe dependence or an opioid use history, buprenorphine-naloxone may be considered. It is important to remember that there are limited studies on the effectiveness of their use for kratom detox. 

Behavioral & Aftercare

Individuals with kratom addiction benefit from a variety of supportive measures, including:

  • Cognitive Behavioral Therapy (CBT) and Motivational Interviewing (MI)
  • Contingency management and peer support groups
  • Step down to IOP/Outpatient programs
  • Personalized relapse prevention plan for sustained recovery

Kratom Detox Plan (Download The Free Kratom Detox Protocol PDF)

Creating a structured kratom detox plan helps individuals safely taper their use while minimizing withdrawal symptoms. The best way to detox from kratom is through a program that offers medical supervision and a personalized kratom detox protocol. 

Download the free Kratom Detox Protocol, a step-by-step taper and symptom-relief checklist you can bring to your clinician to guide your recovery journey. 

Kratom Detox Protocol: Your Daily Recovery Plan

What’s inside:

  • Clinician guided taper frameworks
  • Medications and comfort aids checklist
  • Red flag symptoms to monitor
  • 7 day symptoms tracking sheet
  • Aftercare plan template for long term recovery

Safety Reminder: The FDA warns against self treating for opioid withdrawal with kratom. Always consult a healthcare professional when deciding on a safe detoxification method.

Find Kratom Detox Centers & Rehab for Kratom (Best in the U.S.)

If you’re searching for a kratom detox center near you or other reputable kratom rehab centers, these U.S. facilities provide safe, evidence based care for kratom dependence. Each offers medical detox, withdrawal management and ongoing rehab.

  • The Rehab House – Denver, CO:
    • Comprehensive kratom detox in Denver with residential and outpatient options.
  • Gateway Foundation – Chicago, IL:
    • Licensed Chicago kratom rehab offering full continuum and therapy.
  • Coleman Institute – Multiple U.S. Cities: 
    • Five-day outpatient kratom detox treatment using the Coleman method.
  • Sandstone Care – CO, MD, VA, IL:
    • Medical kratom detox center with dual diagnosis and holistic care.
  • The Last Resort Recovery – Austin, TX:
    • Men-only Austin kratom detox with residential rehab and aftercare.
  • Zinnia Health – Nationwide:
    • National network offering kratom rehab near you with medical detox and mental health support.

Cost, Insurance, & Access for Kratom Rehab

When looking for a kratom detox center, understanding the cost of detox and insurance coverage is essential. Many commercial health plans cover medically supervised detox, though coverage for kratom specific treatment varies.

Financial aid or sliding scale options may also be available.

Because kratom isn’t FDA-approved, benefits differ by policy, so verifying coverage before admission is key.

  • Confirm whether the detox center is in network or out of network.
  • Ask about preauthorization requirements for detox or rehab.
  • Request an itemized cost estimate for medical detox and therapy.
  • Check if your plan includes MOUD coverage under SAMHSA opioid treatment standards.

Rehab for Kratom FAQS

How Long Does Kratom Stay in Your System?

Kratom detection varies due to dosage, frequency and metabolism. While it’s not found on standard drug panels, specialized tests may detect it for several days. 

Can You Detox From Kratom at Home?

At home, kratom detox may be possible for mild cases, but medical supervision lowers the risks of withdrawal complications and relapse. 

What’s The Best Way to Detox from Kratom?

A clinician guided taper or supervised medical detox with aftercare planning offers the safest kratom detox timeline. Some cases may benefit from medication assisted treatment (MAT).

Ready to Start?

Looking for a kratom detox center? You don’t have to suffer from kratom addiction alone. Call the 24/7 helpline at 800-996-6135 for a confidential assessment. We’ll match you with a trusted kratom detox center and help you understand your insurance coverage.


Download the Kratom Detox Protocol: Kratom Detox Protocol: Your Daily Recovery Plan


You don’t need to recover from kratom alone. Call now.

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Written by: Gwendolyn Henderson

Gwendolyn Henderson brings 26 years of extensive experience in field of Mental & Behavioral Health. She has served as an Executive Director, CEO, Vice-President and Consultant for Behavioral Health facilities. In addition, Gwen has provided services as a clinician, case manager and various other roles supporting individuals and families.   

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