South Dakota’s overdose crisis looks unlike most of the country. Throughout the state, methamphetamine and fentanyl drive nearly equal shares of deaths, rather than fentanyl alone. In fact, in 2024, methamphetamine was involved in 42 percent of overdose deaths statewide, which was more than any other single drug. The state has responded with programs like Intensive Methamphetamine Treatment, a long-term evidence-based program specifically for people with severe methamphetamine use disorder, something few states offer as a distinct treatment track.
Unfortunately, the burden of this crisis falls unevenly across the population. American Indians in South Dakota die of overdose at a rate 4.4 times higher than white residents. To help combat this problem, seven of the state’s 39 substance use grant programs are specifically directed toward tribal communities.
South Dakota’s substance use disorder treatment programs are accredited by the Department of Social Services, Division of Behavioral Health, through its Office of Licensing and Accreditation, under Administrative Rule 67:61. Chemical dependency treatment facilities that provide medical detox are separately licensed as health care facilities by the South Dakota Department of Health.
Anyone researching detox should know that recent state data shows overdose deaths declining for a second straight year, even as opioid-involved deaths ticked upward in 2025, a sign the picture keeps shifting substance by substance.
