Detroit sits at the center of one of Michigan’s most acute overdose crises. In fact, the city accounts for more than 15% of Michigan’s total opioid deaths despite representing a fraction of the state’s population.
Treatment and detox facilities operating in Detroit are licensed and regulated by the Michigan Department of Licensing and Regulatory Affairs (LARA), which oversees substance use disorder programs statewide. They must also comply with standards set by the Michigan Department of Health and Human Services (MDHHS).
Additionally, local behavioral health coordination falls under the Detroit Wayne Integrated Health Network (DWIHN), the publicly funded managed care entity for Wayne County. DWIHN operates a 24/7 access line at 800-241-4949 that can match residents with detox, residential or outpatient care based on their coverage and immediate needs.
So, what’s being done? Two major initiatives launched in late 2024 and early 2025 reflect the city’s shift toward a harm-reduction-first approach. In September 2024, Detroit launched its Quick Response Team (QRT), a 24/7 program funded by national opioid settlement dollars that follows up with overdose survivors after Detroit Fire Department intervention and connects them directly to drug and alcohol detox programs.
In April 2025, the Detroit Health Department also deployed 25 Harm Reduction Wellness Stations across neighborhoods with the highest overdose rates, stocked with free naloxone kits, fentanyl test strips and xylazine test strips.
Of great concern is that Wayne County’s fentanyl-contaminated drug supply also now increasingly contains adulterants, including xylazine and medetomidine, a veterinary tranquilizer detected in Wayne County overdose deaths beginning in 2024. Both suppress respiration and do not respond to naloxone.
People seeking detox in Detroit should tell intake staff about any recent exposure to these substances, as withdrawal management protocols may need to account for polysubstance dependency.
