Kentucky runs its substance use system through the Cabinet for Health and Family Services (CHFS). The Office of Inspector General licenses every detox and treatment facility in the state as an Alcohol and Other Drug Entity under Administrative Regulation 908 KAR 1:370.
The Department for Behavioral Health, Developmental and Intellectual Disabilities sets clinical standards and coordinates care. Anyone choosing a detox center can start with the KY HELP Statewide Call Center at 1-833-859-4357, free and answered around the clock.
Kentucky pairs a growing treatment network with a deep public safety net. The state expanded Medicaid, and Kentucky Medicaid covers the full continuum of substance use care, delivered through managed care organizations.
Kentucky has also invested heavily in overdose response, funding a statewide naloxone program and one of the South’s most established networks of syringe service programs run through local health departments.
These efforts are showing results. Kentucky overdose deaths fell 30.2 percent in 2024, the largest single-year drop in state history and the third straight annual decline.
Fentanyl still drives the crisis, which is why medically supervised detox matters. Admission usually begins with an assessment that assigns an American Society of Addiction Medicine (ASAM) level of care to match the setting to a person’s needs.

